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Literature summary for 1.1.1.17 extracted from
- Establishment and application of CRISPR interference to affect sporulation, hydrogen peroxide detoxification, and mannitol catabolism in the methylotrophic thermophile Bacillus methanolicus (2019), Appl. Microbiol. Biotechnol., 103, 5879-5889 .
Application
| Application | Comment | Organism |
|---|---|---|
| analysis | application of CRISPRi-dCas9 technique for gene repression | Bacillus methanolicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bacillus methanolicus | I3E3X0 | - |
- |
| Bacillus methanolicus MGA3 | I3E3X0 | - |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| BMMGA3_01075 | - |
Bacillus methanolicus |
| MtlD | - |
Bacillus methanolicus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | when the mannitol-1-phosphate 5-dehydrogenase gene MtlD is targeted by CRISPRi, mtlD RNA levels, and MtlD specific activities in crude extracts are decreased to about 50 %, which results in reduced biomass formation from mannitol | Bacillus methanolicus |
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